Tuesday, November 11, 2014

Chapter 8: So Where Does this Leave us?


When Raphael Mechoulam discovered the ECS in 1964, he opened the doors to the potential medicinal effects of marijuana. Since then, there have been numerous studies prevalent to the effects of medical marijuana on the human brain. In the article from Chapter 4, Cannabinoid Effects on Anxiety-Related Behaviors and Hypothalamic Neurotransmitters, the side effects of THC are discussed (ArĂ©valo et al. 2001). THC one of the many cannabinoids extracted from the marijuana flower of a female plant, which proves to cause some psychoactive effects and short-term anxiety. Some of the other organic properties in marijuana include CBD, CBC, CBN, CBG and THCV, each possibly exhibiting crucial roles as anti-psychotics. It is interesting to learn that marijuana has been used for both medicinal and mood-altering purposes since 7000 B.C.E. Branching off of that, we start to think about the purpose of this plant is in relation to medicine and treatment. The article in Chapter 5, titled Modulation of the Endogenous Cannabinoid System [ECS] as a Therapeutic Target in the Treatment of Mental Health Disorders, focuses directly on how effective medical marijuana can be in treating psychological disorders (Allen et al. 2013). From the previous chapter, it was determined THC should be at a lower content when treating psychological disorders, due to the side effects. Here, Allen et al. have claimed that “the ECS could be involved in regulating emotional memory and this may explain why we see antidepressant effects with THC administration”. This article was written a year ago, which was twelve years after the previous article. It is interesting to see how science changes and develops so rapidly.


 

In order for the effects of medical marijuana on patients with psychological disorders to be fully understood, more research needs to be conducted. In attempt to undergo research on this topic, Dr. Sue Sisley (mentioned in Chapter 7) uses previous knowledge of medical marijuana to design and implicate a study conducted on veterans suffering from PTSD. Because marijuana is categorized as a schedule 1 substance, Dr. Sisley runs into a complicated process of approval to conduct a study on human patients. A quote given by Governor Lincoln Chafee of Rhode Island brings up a good point, “It defies logic in this day and age that marijuana is still in schedule 1 alongside heroin and LSD when there is so much testimony to what relief medical marijuana can bring”. It is important to understand that the medical marijuana has yet to be linked to serious health risks, and the benefits definitely outweigh them.


Medical marijuana proves to be a credible treatment in many fields of medicine. The cannabinoids produced by the marijuana plant have therapeutic effects and can help patients suffering from psychological disorders. Cannabinoids, such as THC, CBD, CBN, CBG and CBC, can be used to alter the function of the ECS through agonistic effects in patients suffering from affective disorders like bipolar disorder, major depressive disorder, dysthymic disorder and cyclothymic disorder. In theory, scientists believe that medical marijuana can treat many other psychological disorders like eating disorders, mood disorders, somatoform disorders, sleep disorders, anxiety disorders and personality disorders. This type of pharmacotherapy could be of much use in patients suffering from any of these disorders. Along with psychotherapy, medical marijuana will increase the quality of life and ease the daily struggles that come with most psychological disorders. This topic is so interesting and I am definitely intrigued to track more research being done on the medicinal properties this plant beholds!


Resources:
http://ac.els-cdn.com/S0091305701005780/1-s2.0-S0091305701005780-main.pdf?_tid=97e3eac8-4f1e-11e4-93d0-00000aacb35f&acdnat=1412795534_f9189ed7405c60a1fe57a2d078254b05